Transcranial Magnetic Stimulation

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Transcranial magnetic stimulation (TMS) is a non-invasive and relatively safe technology where electromagnetic currents in a coil produces magnetic pulses which crosses the cranium and induces neuron depolarization (Defrin et al. 2007). Magnetic stimulation of the motor cortex has been shown to attenuate post-stroke pain (Migita et al. 1995).

Table 17: Transcranial Magnetic Stimulation


Jette et al. (2013) found individuals receiving active rTMS had significant reduction in pain intensity up to 48 hours post treatment. Defrin et al. (2007) found that both real and sham TMS stimulated treatments significantly reduced pain although the real TMS treatment resulted in a much greater reduction in pain and depression scores at follow-up.


There is level 1a evidence (from two randomized controlled trials; Jette et al. 2013; Defrin et al. 2007) that transcranial magnetic stimulation significantly reduced post-SCI neuropathic pain significantly over the long-term.

  • Transcranial magnetic stimulation reduces post-SCI neuropathic pain.