Venous Thromboembolism Table 8 Studies Evaluating Low Molecular Weight Heparin vs. Unfractionated Heparin

Author/Year

N
& Type of Study

Treatments

Group 1                         Group 2

Results

SCI Thromboprophylaxis Investigators 2003a

107
RCT

LDUH + mechanical methods LMWH (Enoxaparin) +

SCI Thromboprophylaxis Investigators 2003b

119
Prospective Controlled Trial
LDUH LMWH (Enoxaparin)

+

Arnold et al. 2010 24
Case Control
LDUH LMWH (Enoxaparin)

Thumbakit et al. 2002

173
Case Control
LDUH + warfarin LMWH (Enoxaparin)

Worley et al. 2008

90
Case Control
LDUH LMWH (Dalteparin)

Maxwell et al. 2002

111
Case Series
LDUH + mechanical methods LMWH

+

Green et al. 1990

32 RCT

LDUH

LMWH

+

Green et al. 1994 48 Pre-Post LDUH LMWH +

+ Indicates LMWH more effective than LDUH; – Indicates no significant difference; – – Indicates LDUH more effective

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