Table 30 Localized Cooling for Treatment of Pressure Injuries

Author Year

Research Design
Sample Size

Methods Outcome

Tzen et al. 2013


Prospective Controlled Trial


Population: Mean age: 35.79 yr; Gender: males=20, females= 8; Level of injury (ASIA): grade A or B=14, control group=14.

Intervention: All subjects were tested under three conditions: pressure with fast cooling (-4 degrees Celsius/min), pressure with slow cooling (-33 degrees Celsius) and pressure with no cooling.

Outcome Measures: Reactive hyperemia and its spectral densities in the metabolic, neurogenic and myogenic frequency ranges.

1.     Reactive hyperemia was greater in pressure only when compared to the cooling conditions in the control group.

2.     No change in spectral densities for both cooling conditions in SCI or control group.

3.     Neurogenic spectral density increased without cooling for control group.

4.     In SCI patients, no difference noted in reactive hyperemia in any conditions.

5.     Metabolic and myogenic spectral densities increased without cooling and all spectral densities increased with slow cooling for the SCI group.

6.     No change in all spectral densities with fast cooling.