PLIMF therapy uses magnetic fields to increase oxygen levels and decrease toxic by-products of inflammation by increasing local blood flow (Durovic et al. 2009).
Durovic et al. (2009) randomly assigned 29 SCI patients to a control group or treatment group. Both received range of motion and exercise therapy; however, only the treatment group received PLIMF therapy an average of seven weeks post injury for four weeks. The study showed no incidence of HO in the treatment group yet a 33% incidence in the control group (p<0.04).
There is Level 1b evidence (from one RCT; Durovic et al. 2009) that Pulse Low Intensity Electromagnetic Field therapy is an effective prophylaxis of HO post SCI
Pulse low intensity electromagnetic field therapy is effective in preventing heterotopic ossification post spinal cord injury.