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Phosphodiesterase Type 5 Inhibitors to Treat Erectile Function

What is the evidence for Phosphodiesterase Type 5 Inhibitors in the treatment for erectile dysfunction?
1. Phosphodiesterase Type 5 Inhibitors (PDE5i) can be used safely and effectively for treatment of erectile dysfunction (ED) in men with SCI and are recommended as first-line treatment.
2. Men with tetraplegia or high-level paraplegia should be cautioned about the possibility of experiencing postural hypotension for several hours after use of PDE5i.
3. Intracavernosal (penile injectable) medications (ICI) are very effective for the treatment of ED in men with SCI and may be used with careful dose titration and some precautions.

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